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Molnupiravir not to be used in Covid-19 clinical management protocol: ICMR

PTI
Updated: January 11th, 2022, 16:59 IST
in Coronavirus, National, Sci-Tech
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Molnupiravir
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New Delhi: The Indian Council of Medical Research’s (ICMR) National Task Force for Covid-19 has decided against including anti-viral drug Molnupiravir in the Clinical Management Protocol for the disease, official sources said Tuesday. The experts of the task force cited safety concerns and argued that Molnupiravir was not of much benefit in Covid-19 treatment to arrive at the decision in a meeting held Monday.

According to the Health Ministry, Molnupiravir is an antiviral drug that inhibits SARS-CoV-2 replication by viral mutagenesis. This anti-Covid pill got the Drug Regulator General of India’s approval December 28 for restricted use in emergencies.

Also read: Molnupiravir no magic drug, says AIIMS doctor

“Members of the National Task Force for Covid-19 were not in favour of including the drug in the national treatment guidelines citing that it does not have much benefit in the treatment of coronavirus infection and that there were safety concerns,” an official source said Tuesday.

ICMR chief Dr Balram Bhargava had last week said that Molnupiravir has major safety concerns. He added that WHO and the United Kingdom have not included it for treatment.

“We have to remember that this drug has major safety concerns. It can cause teratogenicity, mutagenicity and cartilage damage. It can damage the muscles also. Contraception will have to be done for three months for male and female if this drug is given because the child born could be problematic due to teratogenic influence,” Bhargava had said.

According to conditions, the drug should be sold by retail only under the prescription of medical specialists and the recommended dose should be 800 mg twice daily for five days.

 

Tags: Anti-viralCOVID-19drugICMRMolnupiravirWHO
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